May 30, 2024


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Endocannabinoid System & Medical Marijuana:

3 min read

With the growing popularity of medical marijuana strains and other related products, people are showing interest in educating themselves about the working and effects of medical marijuana. And at some point, they are getting the best support through the information available over different search engines. 

However, reading about medical marijuana is not enough to learn the details of its working. To learn about medical marijuana and its products, it is always best to see a medical marijuana doctor online in Ohio. 

The best and experienced pain management doctors in Ohio can easily guide you through everything about medical marijuana and how it works. 

Moving on, in this write-up, we have added basic information about medical marijuana and how it engages with our biosystem. Read on!

Medical marijuana engages with our endocannabinoid system (ECS)- it is a system responsible for our overall functioning. Before learning how medical marijuana interacts with ECS, let’s learn what the endocannabinoid system is. 

Endocannabinoid System:

The endocannabinoid system is a complicated cell-signaling system present in the human body. Though experts are still researching and learning about ECS, according to the available reports and studies, the Endocannabinoid system plays an important role in regulating a wide range of functions and processes, including sleep, appetite, mood, reproduction and fertility, and more. 

How Does It Work?

The endocannabinoid system (ECS) involves three main components- endocannabinoids, receptors, and enzymes. All these different components works in different way. Take a look!


Endocannabinoids are the cannabinoids present in our bodies. These are the little molecules made by our body- these molecules are quite similar to cannabinoids naturally produced by our body. These cannabinoids work for the overall biosystem. These cannabinoids helps out internal functions to run smoothly. 


Endocannabinoid receptors are found through our body-endocannabinoids bind these receptors to signal that the endocannabinoid has to take action. There are two main endocannabinoid receptors;

CB1 receptors- mostly found in the central nervous system. 

CB2 receptors- these are found in the peripheral nervous system. 

Endocannabinoids can bind to any receptors- the main effects is produced to enhance the immune cells and relieve pain. 


Enzymes are mainly responsible for breaking down endocannabinoids when they are out of their main function. As per the studies; there are two main enzymes responsible;

  • Fatty acid amide hydrolase- it is mainly known for breaking down AEA.
  • Monoacylglycerol acid lipase- it is known for breaking down 2-AG.

 What Are the Main Functions Of ECS?

The ECS is a complicated structure that is responsible for all the potential functions;

  • appetite and digestion
  • metabolism
  • chronic pain
  • inflammation and other immune system responses
  • mood
  • learning and memory
  • motor control
  • sleep
  • cardiovascular system function
  • muscle formation
  • bone remodeling and growth
  • liver function
  • reproductive system function
  • stress
  • skin and nerve function

How Medical Marijuana Does Interacts With The ECS?  

When you engage with medical marijuana, its cannabinoids come in contact with the ECS system. It quickly connects with the endocannabinoid receptors through the brain and body. This interaction interferes with the ability of natural cannabinoids and enhances their natural working. 

According to several studies, when marijuana interacts binds with CB1 and CB2, it enhances the overall body functions. 

How Does THC Interact With The ECS?

Tetrahydrocannabinol (THC) is one of the main and most popular cannabinoids found in marijuana plants. It comes with psychotropic properties. When you interact with THC, it engages with your ECS by binding the receptors. Its interaction is highly powerful as it has the ability to bind both CB1 and CB2 receptors.  

This interaction of both receptors with THC enables it to have a wide range of effects on our biosystem. In simple words, it stimulates that overall functioning. However, the effects may vary depending on the dose of THC you interact with. 

Note: THC is known for psychotropic properties, which means it has the capability to possess high. Therefore, when you engage with the right doses of THC recommended by the Medical Marijuana Doctor Online in Ohio, you receive the best results. 

Moving on, before adding the medical marijuana products to your routine, ensure to consult an expert of the medical marijuana doctors online in Ohio for the complete and best guidance. We have just given an overview of the interaction of medical marijuana with the endocannabinoid system, but there is a lot more to learn that we will discuss in our coming blogs. 

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